Inflammation and Infection in Critical Care Medicine

نویسندگان

  • Jesús F Bermejo-Martin
  • Ignacio Martín-Loeches
  • Steven Bosinger
چکیده

1 Laboratorio de Ciencias Biomédicas en Investigación Cĺınica (CBIC), Hospital Cĺınico Universitario de Valladolid, IECSCYL-SACYL, Avenida Ramón y Cajal 3, 47005 Valladolid, Spain 2 Critical Care Centre, Corporació Sanitària i Universitaria Parc Tauĺı—Hospital de Sabadell, Institut Universitari UAB Ciber Enfermedades Respiratorias, Parc Tauĺı 1, Sabadell, 08208 Barcelona, Spain 3 Department of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University, Rm 3028 Emory Vaccine Center Building 954, Gatewood Road NE, Atlanta, GA 30329, USA

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Inflammation, a Key Factor in Cancer Ambush

Inflammatory condition is the consequence of defensive mechanism of immune system against viral and bacterial infection, tissue injury, UV radiation, stress and etc. Persistently acute inflammation leads to chronic phase which is characterized by production of pro-inflammatory mediators from T cells. These molecules (e.g. IL-6, TNF-&alpha, IL-1&beta and IL-17) are mostly pleiotropic cytokines i...

متن کامل

The role of cytokine and its relation to depression and infection complications in pediatric cancer

Inflammation plays a critical role in the progression of cancer in children. On the other hand, children with cancer experience abnormal activation of the inflammatory system. Moreover, it is known that these patients have a predisposition to depression. According to studies, moderate to severe depression was observed in about 63% of children with cancer and acute illness. Therefore, identifyin...

متن کامل

TNF-α iNOS Augmentation Due to Macrophages and Neutrophils Activity in Samples from Patients in Intensive Care Unit with COVID-19 Infection

Background and Aims: Cells and secreted molecules by the innate immune system are the essential factors in the pathogenesis and determining the severity of inflammation in COVID-19 patients. Severe inflammation results from increased activity of neutrophils, macrophages, and other cells with their products. Inflammatory cytokines such as tumor necrosis factor-α (TNF-α) increases the severity an...

متن کامل

The Epidemiology, Therapeutic Patterns, Outcome, and Challenges in Managing Septic Shock in a Sub-Saharan African Intensive Care Unit: A Cross-Sectional Study

Background: Septic shock (SS) is a health priority in sub-Saharan Africa. However, there is a dearth of data in this regard. Objective: This study aimed to determine the epidemiology, therapeutic patterns, outcome, and challenges in managing SS in a tertiary intensive care unit (ICU) of sub-Saharan Africa. Methods: The hospital file...

متن کامل

An Unusual Presentation of Granulomatosis with Polyangiitis

The granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis, is a pauci-immune vasculitis involving small- and medium-sized blood vessels. Classically, the patients inflicted with this disease present with a triad of necrotizing granulomatous inflammation of the respiratory tract, cutaneous necrotizing vasculitis, and glomerulonephritis (GN). The antinuclear (ANA) and...

متن کامل

Monocyte TREM-1 membrane expression in non-infectious inflammation

Sterile or non-infectious inflammation and severe infection are accompanied by very similar events. Damage (or danger)-associated molecular patterns and pathogen-associated molecular patterns trigger the release of inflammatory mediators and modulate the expression of cell surface receptors. The increased expression on monocytes and neutrophils of triggering receptor expressed on myeloid cells ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 2014  شماره 

صفحات  -

تاریخ انتشار 2014